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【Seracare產(chǎn)品介紹】

編號(hào)	英文名稱	中文名稱
JL-FA-01	Amebiasis (AME)	阿米巴病
JL-FA-02	Allergens, Rast scores	過敏原，放射性過敏原吸收實(shí)驗(yàn)。指對(duì)特定的人群引起免疫反應(yīng)或者過敏反應(yīng)的食品中的蛋白質(zhì)
JL-FA-03	Allergens, Rast scores negative	過敏原，放射性過敏原吸收實(shí)驗(yàn)陰性
JL-FA-04	Anti-cyclic citrullinated peptide Antibody (CCP) Arthritis	抗環(huán)瓜氨酸肽抗體
JL-FA-05	ASCA Saccharomyces Cerevi	人抗釀酒酵母抗體（ASCA）
JL-FA-06	Aspergillis	麴菌病
JL-FA-07	Beta 2 Glycoprotein	β2糖蛋白
JL-FA-08	Beta 2 Glycoprotein IgM	β2糖蛋白 IGM
JL-FA-09	Bordela Pertussis	百日咳桿菌
JL-FA-10	Bordela Pertussis IgM	百日咳桿菌 IGM
JL-FA-11	C-ANCA	C-抗中性粒細(xì)胞胞漿抗體（ANCA)
JL-FA-12	Cardiolipin	心肌磷脂
JL-FA-13	Cardiolipin IgA	心肌磷脂 IGA
JL-FA-14	Cardiolipin IgG	心肌磷脂 IGG
JL-FA-15	Cardiolipin IgM	心肌磷脂 IGM
JL-FA-16	Cerebral Spinal Fluid	腦脊髓液
JL-FA-17	Chagas	恰加斯病/南美錐蟲
JL-FA-18	Chlamydia	衣原體
JL-FA-19	Chlamydia IgA	衣原體IGA
JL-FA-20	Chlamydia IgG	衣原體IGG
JL-FA-21	Chlamydia IgM	衣原體IGM
JL-FA-22	Chlamydia Neg	衣原體陰性
JL-FA-23	Clotting Factor C3	凝固因子C3
JL-FA-24	Clotting Factor C4	凝固因子C4
JL-FA-25	Coccidiodes	球孢菌
JL-FA-26	Cytomegalovirus (CMV) Neg	巨細(xì)胞病毒抗體陰性
JL-FA-27	CMV IgG	巨細(xì)胞病毒 IGG陽性
JL-FA-28	CMV IgM VCA	巨細(xì)胞病毒 IGM 陽性
JL-FA-29	C-Reactive Protein (CRP)	C-反應(yīng)蛋白質(zhì)
JL-FA-30	Dengue Fever	登革熱
JL-FA-31	Dengue Fever IgM	登革熱 IGM
JL-FA-32	DS (Double Stranded) DNA	雙鏈脫氧核糖核酸
JL-FA-33	EBNA (Epstein-Barr nuclear antigen) IgG	EB病毒核抗原 IGG
JL-FA-34	EBNA (Epstein-Barr nuclear antigen) IgM	EB病毒核抗原 IGM
JL-FA-35	Epstein Barr Virus (EBV) Negative Plasma	EB病毒陰性血漿
JL-FA-36	Epstein Barr Virus (EBV) EA IgM	EB病毒早期抗原 IGM
JL-FA-37	Epstein Barr Virus (EBV) VCA IgM	EB病毒殼蛋白 IGM
JL-FA-38	Epstein Barr Virus (EBV) EA IgG	EB病毒早期抗原 IGG
JL-FA-39	EMA (Endomysial Antibodies)	肌內(nèi)膜
JL-FA-40	Gliadin	麩蛋白,麥醇溶蛋白,麥膠蛋白
JL-FA-41	Gliadin IgG	麥醇溶蛋白 IGG
JL-FA-42	Gliadin IgA	麥醇溶蛋白 IGA
JL-FA-43	Glomerular Basement Membrane (GBMA)	腎小球基底膜病
JL-FA-44	Helicobacter pylori IgA	幽門螺旋桿菌IGA
JL-FA-45	Helicobacter pylori IgG	幽門螺旋桿菌IGG
JL-FA-46	Helicobacter pylori IgM	幽門螺旋桿菌IGM
JL-FA-47	Helicobacter pylori Negative	幽門螺旋桿菌陰性
JL-FA-48	Helicobacter pylori Positive Plasma	幽門螺旋桿菌陰性血漿
JL-FA-49	Hepatitis A Virus (HAV) Pos. Plasma	甲型肝炎病毒陽性血漿
JL-FA-50	Hepatitis A Virus (HAV) IgM	甲型肝炎病毒IGM
JL-FA-51	Hepatitis B Core (HBc) IgG	乙型肝炎病毒核心 IGG
JL-FA-52	Hepatitis B Core (HBc) IgM	乙型肝炎病毒核心 IGM
JL-FA-53	Anti Hbe (Antibody to HBV antigen)	乙肝抗體
JL-FA-54	Hepatitis Delta Virus	丁型肝炎病毒
JL-FA-55	HBeAg (HBV e antigen)	乙肝 E抗原
JL-FA-56	anti-HBs (HBV surface antibody)	乙肝表面抗體
JL-FA-57	Hepatitis B (HBsAg) "Chronic"	乙型肝炎（乙肝表面抗原）“慢性病
JL-FA-58	HBsAg (HBV surface antigen) Serum	乙肝表面抗原血清
JL-FA-59	HBsAg (AD)	乙肝表面抗原（AD）
JL-FA-60	HBsAg (AY)	乙肝表面抗原（AY）
JL-FA-61	HBV Positive Plasma	乙肝陽性血漿
JL-FA-62	HBV DNA Plasma	乙肝DNA血漿
JL-FA-63	HBV DNA Serum	乙肝DNA血清
JL-FA-64	HBV DNA type A	A型乙肝DNA
JL-FA-65	HBV DNA type B	B型乙肝DNA
JL-FA-66	HBV DNA type C	C型乙肝DNA
JL-FA-67	HBV DNA type D	D型乙肝DNA
JL-FA-68	HBV DNA type E	E型乙肝DNA
JL-FA-69	HBV DNA type F	F型乙肝DNA
JL-FA-70	HBV Antibody HCV Antibody Plasma CO-INFECTED	乙肝和丙肝聯(lián)合感染血漿
JL-FA-71	HCV (Hepatitis C Virus) Antibody	丙型肝炎抗體
JL-FA-72	HCV Core Antigen Positive	丙肝核心抗原陽性
JL-FA-73	HCV RNA PLASMA Genotype 1	基因1型丙肝RNA 血漿
JL-FA-74	HCV RNA PLASMA Genotype 2	基因2型丙肝RNA 血漿
JL-FA-75	HCV RNA PLASMA Genotype 3	基因3型丙肝RNA 血漿
JL-FA-76	HCV RNA PLASMA Genotype 4	基因4型丙肝RNA 血漿
JL-FA-77	HCV RNA PLASMA Genotype 5	基因5型丙肝RNA 血漿
JL-FA-78	HCV RNA PLASMA Genotype 6	基因6型丙肝RNA 血漿
JL-FA-79	HCV Riba single band	丙肝免疫印跡單波段
JL-FA-80	HCV RIBA Pos. (multiple bands)	丙肝免疫印跡陽性多波段
JL-FA-81	HCV Negative	丙肝陰性
JL-FA-82	HCV RNA Pos (quantitative)	丙肝RNA陽性（定量）
JL-FA-83	Hepatitis E	戊型肝炎
JL-FA-84	Herpes Simplex Virus (HSV)1/2 Positive Plasma	單純性皰疹病毒1/2陽性血漿
JL-FA-85	Herpes Simplex Virus (HSV) 1 Negative Plasma	單純性皰疹病毒1 陰性血漿
JL-FA-86	Herpes Simplex Virus (HSV) 1 IgG	單純性皰疹病毒1 IGG
JL-FA-87	Herpes Simplex Virus (HSV 1) IgM	單純性皰疹病毒1 IGM
JL-FA-88	Herpes Simplex Virus (HSV) 2 IgG	單純性皰疹病毒2 IGG
JL-FA-89	Herpes Simplex Virus (HSV) 2 IgM	單純性皰疹病毒2 IGG
JL-FA-90	Histone	組蛋白
JL-FA-91	Human Anti Mouse Ab (HAMA)	人抗鼠抗體
JL-FA-92	Human immunodeficiency virus (HIV) 1 Neg	HIV I 陰性
JL-FA-93	anti Human immunodeficiency virus (HIV) 1 Plasma	抗HIV I 血漿
JL-FA-94	anti Human immunodeficiency virus (HIV) 1 Serum	抗HIV I 血清
JL-FA-95	anti Human immunodeficiency virus (HIV) 2 Western Blot Tested	抗HIV 2 免疫印跡
JL-FA-96	anti Human immunodeficiency virus (HIV) 1/2 2 HIV (+)	抗HIV 1/2 2 HIV陽性
JL-FA-97	Human immunodeficiency virus (HIV) Ag	HIV抗原
JL-FA-98	HIV RNA (quantitative) Plasma	HIV RNA 定量血漿
JL-FA-99	HIV RNA (quantitative) Serum	HIV RNA 定量血清
JL-FA-100	HIV1 Subtype A	HIV1 亞型A
JL-FA-101	HIV1 Subtype B	HIV1 亞型B
JL-FA-102	HIV1 Subtype C	HIV1 亞型C
JL-FA-103	HIV1 Subtype D	HIV1 亞型D
JL-FA-104	HIV1 Subtype E	HIV1 亞型E
JL-FA-105	HIV1 Subtype F	HIV1 亞型F
JL-FA-106	HIV1 Subtype G	HIV1 亞型G
JL-FA-107	HIV1 Subtype H	HIV1 亞型H
JL-FA-108	HIV1 Subtype J	HIV1 亞型J
JL-FA-109	HIV1 Subtype K	HIV1 亞型K
JL-FA-110	HIV1 Group O	HIV1 亞型O
JL-FA-111	Human immunodeficiency virus (HIV) 2 Antibody Plasma	HIV 2 抗體血漿
JL-FA-112	Human immunodeficiency virus (HIV) 2 Antibody Serum	HIV 2 抗體血清
JL-FA-113	HPV (Human Papiloma Virus) Negative	人乳狀瘤病毒HPV陰性
JL-FA-114	HPV (Human Papiloma Virus) Positive	人乳狀瘤病毒HPV陽性
JL-FA-115	Human immunodeficiency virus (HIV) Antibody HCV Antibody Plasma COINFECTED	HIV 抗體 HCV
JL-FA-116	Human T-cell Lymphotropic Virus (HTLV) I/II	人嗜T淋巴細(xì)胞病毒(HTLV) I/II
JL-FA-117	Human T-cell Lymphotropic Virus (HTLV) I	人嗜T淋巴細(xì)胞病毒(HTLV) I
JL-FA-118	Human T-cell Lymphotropic Virus (HTLV) II	人嗜T淋巴細(xì)胞病毒(HTLV) II
JL-FA-119	Jo-1	多發(fā)性肌炎抗原JO-1
JL-FA-120	IgE < 5,000 Ku/L	IgE < 5,000 Ku/L
JL-FA-121	Legionella	軍團(tuán)桿菌屬
JL-FA-122	Leptospira	軍團(tuán)桿菌屬
JL-FA-123	Lyme Disease	萊姆(氏)病:蜱傳播的全身性疾病,常在夏季發(fā)生
JL-FA-124	Lyme IgG	萊姆(氏)病 IGG
JL-FA-125	Lyme IgM	萊姆(氏)病 IGM
JL-FA-126	Lyme Disease Neg	萊姆(氏)病陰性
JL-FA-127	Malaria	瘧疾
JL-FA-128	Mononucleosis (infectious)	單核細(xì)胞增多癥（有傳染性的）
JL-FA-129	Mononucleosis Negative	單核細(xì)胞增多癥陰性
JL-FA-130	Measles Negative	麻疹陰性
JL-FA-131	Measles IgG	麻疹 IGG
JL-FA-132	Measles IgM	麻疹 IGM
JL-FA-133	Microsomal Anti-thyroid peroxidase antibody (TPO) Positive Plasma Standard Titer (typically 1,000-3,000 IU/mL)	微粒體抗甲狀腺過氧化物酶抗體
JL-FA-134	Microsomal Anti-thyroid peroxidase antibody (TPO) Negative Plasma	微粒體抗甲狀腺過氧化物酶抗體
JL-FA-135	Anti-mitochondrial antibody (AMA)	抗線粒體抗體
JL-FA-136	Multiple Sclerosis	多發(fā)性硬化癥
JL-FA-137	Mumps IgG	流行性腮腺炎 IGG
JL-FA-138	Mumps Ab IgM	流行性腮腺炎抗體 IGM
JL-FA-139	Mumps Antibody Negative Plasma	流行性腮腺炎抗體陰性血漿
JL-FA-140	Mumps Antibody Negative Serum	流行性腮腺炎抗體陰性血清
JL-FA-141	Myeloma Plasma	骨髓瘤血漿
JL-FA-142	Myeloma IgA	骨髓瘤IGA
JL-FA-143	Myeloma IgE	骨髓瘤IGE
JL-FA-144	Myeloma IgG	骨髓瘤IGG
JL-FA-145	Myeloma IgM	骨髓瘤IGM
JL-FA-146	Mycoplasma	支原體
JL-FA-147	Mycoplasma Negative	支原體陰性
JL-FA-148	Mycoplasma IgG	支原體IGG
JL-FA-149	Mycoplasma IgM	支原體IGM
JL-FA-150	Mycoplasma PCR	支原體PCR
JL-FA-151	Normal Human Plasma	正常人血漿
JL-FA-152	Normal Human Serum	正常人血清
JL-FA-153	Nuclear Antibody Centromere	核抗體著絲粒
JL-FA-154	Nuclear Antibody, Speckled ANA	核抗體，斑點(diǎn)抗核抗體
JL-FA-155	Nuclear Antibody, Nucleolar ANA	核抗體,核仁抗核抗體
JL-FA-156	Nuclear Antibody, Homogeneous ANA	核抗體，同質(zhì)抗核抗體
JL-FA-157	Nuclear Antiobody, Speckled. (ANA) Negative	核抗體，斑點(diǎn)。抗核抗體陰性
JL-FA-158	P-ANCA (associated neutrophil cytoplasmic antibodies)	相關(guān)的嗜中性粒細(xì)胞胞漿抗體
JL-FA-159	Parietal Cell Antibody (PCA)	胃)壁細(xì)胞抗體
JL-FA-160	Parvo positive plasma	細(xì)小病毒陽性血漿
JL-FA-161	Parvo IgM	細(xì)小病毒 IGM
JL-FA-162	Parvo IgG	細(xì)小病毒 IGG
JL-FA-163	Parvo Negative Plasma	細(xì)小病毒陰性血漿
JL-FA-164	Parvo DNA positive	細(xì)小病毒 DNA 陽性
JL-FA-165	Phospholipid Positive Plasma	磷脂陽性血漿
JL-FA-166	Prothrombin	凝血酶原,凝血因子
JL-FA-167	Rheumatoid Factor (RF) <1000 IU/mL	類風(fēng)濕因子<1000 IU/mL
JL-FA-168	Rheumatoid Factor (RF) 1001-2000 IU/mL	類風(fēng)濕因子1001-2000 IU/mL
JL-FA-169	Rheumatoid Factor (RF) 2001-4000 IU/mL	類風(fēng)濕因子 2001-4000 IU/mL
JL-FA-170	Rheumatoid Factor (RF) 4001-5000 IU/mL	類風(fēng)濕因子 4001-5000 IU/mL
JL-FA-171	Rheumatoid Factor (RF) >5000 IU/mL	類風(fēng)濕因子>5000 IU/mL
JL-FA-172	Ribonucleoprotein (RNP) Positive	核糖核蛋白陽性
JL-FA-173	Rubella Chimeric	風(fēng)疹
JL-FA-174	Rubella Negative	風(fēng)疹陰性
JL-FA-175	Rubella IgG	風(fēng)疹I(lǐng)GG
JL-FA-176	Rubella IgM	風(fēng)疹I(lǐng)GM
JL-FA-177	Rubeola Negative Plasma	風(fēng)疹陰性血漿
JL-FA-178	Rubeola IgG	風(fēng)疹I(lǐng)GG
JL-FA-179	Scleroderma (Scl-70) Pos	膠原沉著病,硬皮病,硬皮癥陽性
JL-FA-180	Scleroderma (Scl-70) Negative	硬皮病陰性
JL-FA-181	Sickle Cell Fresh Whole Blood	鐮刀形紅細(xì)胞新鮮全血
JL-FA-182	Smith (SM)	抗Smith抗體陽性血清（SLE的特征性抗體）
JL-FA-183	SMITH RNP	抗RNP抗體陽性血清（SLE的特征性抗體）
JL-FA-184	Smooth Muscle (ASMA)	抗平滑肌抗體陽性血清
JL-FA-185	Sjogren syndrome antigen A (SSA) Positive	舍格倫綜合征或干燥綜合征抗原A 陽性
JL-FA-186	Sjogren syndrome antigen B (SSB) Positive	舍格倫綜合征抗原B 陽性
JL-FA-187	Sjogren syndrome antigen B (SSB) Negative	舍格倫綜合征抗原B陰性
JL-FA-188	Streptolysin O Ab (ASO)	鏈球菌溶血素O抗體
JL-FA-189	Syphilis (RPR - Rapid Plasma Reagin) Positive Plasma	梅毒（梅毒-快速血漿反應(yīng)）陽性血漿
JL-FA-190	Syphilis (RPR - Rapid Plasma Reagin) Negative Plasma	梅毒（梅毒-快速血漿反應(yīng)）陰性血漿
JL-FA-191	Syphilis/ATA/T. pallidum IgG	梅毒ATA/T，蒼白球IGG
JL-FA-192	Syphilis/ATA/T. pallidum IgM	梅毒ATA/T，蒼白球IGM
JL-FA-193	Systemic Lupus Erythematosus (SLE) Positive	全身性紅斑狼瘡陽性
JL-FA-194	Systemic Lupus Erythematosus (SLE) Negative	全身性紅斑狼瘡陰性
JL-FA-195	TG/TPO Positive (Standard Titer 1,000 - 3000 IU/mL)	甲狀腺球蛋白/甲狀腺過氧化物酶陽性
JL-FA-196	TG/TPO Negative	甲狀腺球蛋白/甲狀腺過氧化物酶陰性
JL-FA-197	TTG (Tissue Transglutaminase)	組織轉(zhuǎn)谷氨酰胺酶
JL-FA-198	TTG (Tissue Transglutaminase) IgA	組織轉(zhuǎn)谷氨酰胺酶 IGA
JL-FA-199	ToRCH (Toxo, Rubella, CMV, HSV) Positive	優(yōu)生優(yōu)育（弓形蟲，風(fēng)疹，巨細(xì)胞，單胞）陽性
JL-FA-200	ToRCH (Toxo, Rubella, CMV, HSV) Negative	優(yōu)生優(yōu)育（弓形蟲，風(fēng)疹，巨細(xì)胞，單胞）陰性
JL-FA-201	Toxoplasmosis (Toxo)	弓形蟲病
JL-FA-202	Toxoplasmosis (Toxo) IgG	弓形蟲病IGG
JL-FA-203	Toxoplasmosis (Toxo) IgM	弓形蟲病IGM
JL-FA-204	Thyroglobulin (TG) Positive Plasma	甲狀腺球蛋白陽性血漿
JL-FA-205	Thyroglobulin (TG) Negative	甲狀腺球蛋白陰性
JL-FA-206	Varicella-Zoster Virus (VZV) Negative	水痘-帶狀皰疹病毒陰性
JL-FA-207	Varicella-Zoster Virus (VZV) IgG	水痘-帶狀皰疹病毒IGG
JL-FA-208	Varicella-Zoster Virus (VZV) IgM	水痘-帶狀皰疹病毒IGM
JL-FA-209	West Nile Virus (WNV)	西尼羅河腦炎病毒
JL-FA-210	West Nile Virus (WNV) IgM	西尼羅河腦炎病毒IGM

美國Seracare

這一成果發(fā)表在美國《科學(xué)轉(zhuǎn)化醫(yī)學(xué)》雜志上。陳萬軍說，他們利用此技術(shù)對(duì)罹患多發(fā)性硬化癥與I型糖尿病的小鼠進(jìn)行治療，讓病鼠取得了長期緩解，接下來他們還將探索此技術(shù)在類風(fēng)濕性關(guān)節(jié)炎治療與異體抗原抗體排斥治療等方面的應(yīng)用前景。
他說，如果動(dòng)物實(shí)驗(yàn)成功，“我們將和臨床醫(yī)生合作把這個(gè)技術(shù)用在自體免疫疾病病人的治療上。盡管仍有很多困難和問題需要解決，但我們有信心zui終會(huì)造福病人。我們不但要和美國醫(yī)生合作，也希望有機(jī)會(huì)和中國醫(yī)生合作”。
南安普敦大學(xué)科學(xué)家的一項(xiàng)研究發(fā)現(xiàn)，神經(jīng)發(fā)生(神經(jīng)再生)，成人大腦的自我修復(fù)機(jī)制，有助于保護(hù)神經(jīng)退行性疾病(如阿爾茨海默氏癥，朊病毒或帕金森氏)的大腦功能。
許多神經(jīng)退行性疾病發(fā)生后，大腦會(huì)逐漸退化和死亡，這往往被視為一種不可阻擋的，不可撤銷的過程。然而，大腦有一些自我修復(fù)的潛力，更新生活在齒狀回中的某些神經(jīng)元的量。齒狀回是一個(gè)簡單的皮層區(qū)域，控制學(xué)習(xí)和記憶的大腦較大功能系統(tǒng)海馬體的一部分。這個(gè)過程被稱為神經(jīng)發(fā)生。
雖然過去的神經(jīng)退行性疾病中已報(bào)道增加神經(jīng)發(fā)生，但其意義尚不清楚?，F(xiàn)在，來自于南安普敦大學(xué)生物科學(xué)中心迭戈戈麥斯 - 尼古拉博士的一個(gè)研究小組，發(fā)現(xiàn)，增加齒狀回的神經(jīng)發(fā)生可部分抵消神經(jīng)元的損傷。
利用小鼠朊病毒疾病的模型，研究人員確定這些新生神經(jīng)元產(chǎn)生的時(shí)間進(jìn)程，以及它們?nèi)绾稳谌氪竽X回路中。雖然這種自我修復(fù)機(jī)制能夠有效維持疾病早期和中間階段的神經(jīng)功能，但是在更高級(jí)的階段中卻無法維持。這突出一個(gè)為了保護(hù)有益增強(qiáng)神經(jīng)發(fā)生的影響的潛在干預(yù)治療的時(shí)間窗口。
戈麥斯 - 尼古拉博士說：“這項(xiàng)研究顯示，大腦的潛能有助于協(xié)調(diào)自我修復(fù)反應(yīng)。繼續(xù)這方面的研究開辟新的途徑，確定哪些特殊信號(hào)有助于促進(jìn)神經(jīng)發(fā)生反應(yīng)的增加，專注于神經(jīng)發(fā)生作為一種促進(jìn)缺失神經(jīng)元再生的治療方法。”
這項(xiàng)研究發(fā)表于《大腦》雜志上，由歐盟第七框架計(jì)劃和醫(yī)學(xué)研究理事會(huì)(MRC)資助。
已知由大腦中的海馬體協(xié)調(diào)學(xué)習(xí)和記憶能力。在誕生之前，大腦的大部分已經(jīng)發(fā)育完畢。此后還要經(jīng)歷兩個(gè)發(fā)育高峰時(shí)期，一個(gè)是兒童期，一個(gè)是青春期，這兩個(gè)階段大腦發(fā)育快速。在過去20年間，研究證實(shí)，成人的神經(jīng)再生主要發(fā)生在海馬體中。
該研究通過一個(gè)動(dòng)物模型發(fā)現(xiàn)，核受體TLX基因過量表達(dá)時(shí)，試驗(yàn)對(duì)象聰明且學(xué)習(xí)起來更快，另外所獲得的信息能持續(xù)得更持久。

美國Seracare

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【公司名稱】 廣州健侖生物科技有限公司
【】楊永漢
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This result was published in the United States, "Science Translational Medicine" magazine. Chen Wanjun said that they use this technology to treat mice with multiple sclerosis and type I diabetes so as to achieve long-term relief of the disease. Next, they will explore the use of this technology in the treatment of rheumatoid arthritis with alloantibodies Exclusion treatment and other aspects of the application prospects.
He said that if the animal experiments were successful, "We will work with clinicians to apply this technology to the treatment of patients with autoimmune diseases, and although there are still many difficulties and problems to solve, we are confident that we will ultimay benefit the patients. Cooperation with American doctors also hope to have the opportunity to cooperate with Chinese doctors. "
A study led by scientists at the University of Southampton found that neurogenesis (neural regeneration), the self-repair mechanism of the adult brain, helps protect neurodegenerative diseases such as Alzheimer's disease, prion or Parkinson's disease Brain function.
After many neurodegenerative diseases occur, the brain gradually degenerates and dies, often as an irresistible and irrevocable process. However, the brain has some potential for self-healing, updating the amount of certain neurons that live in the dentate gyrus. The dentate gyrus is a simple cortical area that controls part of the hippocampus of the greater functional system of learning and memory of the brain. This process is called neurogenesis.
Although neurogenesis has been reported in neurodegenerative diseases in the past, its significance is not clear. Now, a team led by Dr Diego Gomez-Nicola, from the Center for Biological Sciences at the University of Southampton, found that increasing neurogenesis in the dentate gyrus partially offset neuronal damage.
Using a model of mouse prion disease, researchers determine the timing of these newborn neurons and how they integrate into the brain's circuitry. Although this self-healing mechanism can effectively maintain the neurological function of the early and middle stages of the disease, it can not be maintained at a more advanced stage. This highlights a time window for potential interventions to protect the beneficial effects of neurogenesis.
Dr. Gomez-Nicola said: "This study shows that the brain's potential helps to coordinate self-healing reactions." Continuing studies in this area have opened up new avenues to determine which particular signals contribute to promoting an increased neurogenic response , Which focuses on neurogenesis as a treatment for de novo neuron regeneration. "
The study, published in the journal Brain, is funded by the EU's Seventh Framework Program and the Medical Research Council (MRC).
It is known that the hippocampus in the brain coordinates the learning and memory abilities. Before birth, much of the brain has been developed. There are two more developmental periods to follow, one in childhood and one in adolescence, during which time the brain develops rapidly. In the past 20 years, studies have confirmed that adult nerve regeneration occurs mainly in the hippocampus.
The study, based on an animal model, found that when the nuclear receptor TLX gene is overexpressed, subjects are smart and learn faster, and the information they receive lasts longer.

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